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Magnesium

A macromineral involved in over 300 enzymatic reactions, crucial for muscle relaxation, ATP production, and nervous system calm.

Evidence-Based
Fact-Checked
Updated: Oct 10, 2026
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Clinical Profile

Quick Reference

Scientific Rating
5.0
/ 5.0
Standardized Form
Magnesium Bisglycinate, L-Threonate, or Malate

Magnesium stabilizes the ATP molecule, regulates ion channels, and acts as a natural calcium channel blocker to relax muscles. Magnesium Bisglycinate (magnesium bound to the amino acid glycine) is a highly bioavailable chelate that utilizes dipeptide transport channels in the gut, effectively avoiding the osmotic diarrhea common with magnesium oxide or citrate.

Clinical Summary

Universally supported for reducing muscle cramps, improving sleep architecture, and supporting cardiovascular health.

Dosage Guidelines

310mg to 420mg daily.

Safety & Side Effects

High doses of non-chelated forms cause diarrhea. Bisglycinate is highly tolerable.

Known Interactions

Can bind to tetracycline and quinolone antibiotics, reducing their absorption.

Scientific References

Medical Disclaimer

The information provided in this clinical review is for educational and informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

*These statements have not been evaluated by the Food and Drug Administration (FDA). This product or ingredient is not intended to diagnose, treat, cure, or prevent any disease.

Always consult your physician or other qualified health provider with any questions you may have regarding a medical condition, or before beginning any new diet, fitness, supplement, or treatment regimen, especially if you have pre-existing medical conditions or are taking prescribed medications.

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