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HFL Health Findings Lab™

Niacin

Vitamin B3, required for the synthesis of NAD/NADP and widely known for supporting healthy lipid profiles.

Evidence-Based
Fact-Checked
Updated: Oct 02, 2026
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Clinical Profile

Quick Reference

Scientific Rating
4.8
/ 5.0
Standardized Form
Nicotinic Acid or Niacinamide

Niacin is converted into NAD and NADP, coenzymes involved in over 400 cellular reactions, primarily in catabolic energy production. In pharmacological doses, nicotinic acid can significantly lower LDL cholesterol and triglycerides while raising HDL, though it often causes cutaneous flushing.

Clinical Summary

Supported for cardiovascular lipid management and cellular energy.

Dosage Guidelines

14mg to 16mg daily; pharmacological doses range from 500mg to 2,000mg.

Safety & Side Effects

Niacin flush (redness, warmth, itching) with nicotinic acid. High doses can elevate liver enzymes.

Known Interactions

Increases the risk of myopathy when taken with statins.

Scientific References

Medical Disclaimer

The information provided in this clinical review is for educational and informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

*These statements have not been evaluated by the Food and Drug Administration (FDA). This product or ingredient is not intended to diagnose, treat, cure, or prevent any disease.

Always consult your physician or other qualified health provider with any questions you may have regarding a medical condition, or before beginning any new diet, fitness, supplement, or treatment regimen, especially if you have pre-existing medical conditions or are taking prescribed medications.

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