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Magnesium Malate

Magnesium bound to malic acid, clinically utilized to support mitochondrial energy production and alleviate muscular pain.

Evidence-Based
Fact-Checked
Updated: Oct 24, 2026
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Clinical Profile

Quick Reference

Scientific Rating
4.6
/ 5.0
Standardized Form
Magnesium Malate

Magnesium malate combines elemental magnesium with malic acid, a crucial intermediate in the mitochondrial Krebs cycle. This specific combination is highly bioavailable and is heavily favored in clinical protocols for chronic fatigue syndrome and fibromyalgia. By supplying both magnesium for muscle relaxation and malate for ATP production, it targets muscular energy deficits without causing the severe gastrointestinal distress associated with oxide or citrate forms.

Clinical Summary

Commonly recommended and utilized in functional medicine for fibromyalgia, chronic fatigue, and exercise-induced muscle soreness.

Dosage Guidelines

300mg to 400mg daily. Often taken in the morning or early afternoon due to its energy-supporting properties.

Safety & Side Effects

Very well tolerated. Less likely to cause a laxative effect than magnesium citrate.

Known Interactions

Can bind to certain antibiotics in the gut, reducing their absorption.

Scientific References

Medical Disclaimer

The information provided in this clinical review is for educational and informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

*These statements have not been evaluated by the Food and Drug Administration (FDA). This product or ingredient is not intended to diagnose, treat, cure, or prevent any disease.

Always consult your physician or other qualified health provider with any questions you may have regarding a medical condition, or before beginning any new diet, fitness, supplement, or treatment regimen, especially if you have pre-existing medical conditions or are taking prescribed medications.

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