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HFL Health Findings Lab™

Magnesium Hydroxide

An inorganic magnesium salt primarily utilized as a fast-acting osmotic laxative and antacid.

Evidence-Based
Fact-Checked
Updated: Oct 10, 2026
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Clinical Profile

Quick Reference

Scientific Rating
4.2
/ 5.0
Standardized Form
Magnesium Hydroxide Suspension (e.g., Milk of Magnesia)

Magnesium hydroxide is poorly absorbed by the human intestinal tract. Instead of raising systemic magnesium levels for neurological benefits, it remains in the gut lumen where it exhibits a strong osmotic effect, drawing water into the intestines to induce peristalsis. It also chemically neutralizes gastric acid, functioning as a potent over-the-counter antacid.

Clinical Summary

Highly effective for the short-term relief of occasional constipation and acute dyspepsia (heartburn). Not recommended for correcting systemic magnesium deficiency.

Dosage Guidelines

400mg to 1,200mg as an antacid; up to 2,400mg to 4,800mg to induce a laxative effect.

Safety & Side Effects

Diarrhea, abdominal cramping, and potential fluid/electrolyte imbalances with chronic overuse.

Known Interactions

Alters gastric pH, which can significantly reduce the absorption of medications requiring an acidic environment (e.g., ketoconazole, iron).

Scientific References

Medical Disclaimer

The information provided in this clinical review is for educational and informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

*These statements have not been evaluated by the Food and Drug Administration (FDA). This product or ingredient is not intended to diagnose, treat, cure, or prevent any disease.

Always consult your physician or other qualified health provider with any questions you may have regarding a medical condition, or before beginning any new diet, fitness, supplement, or treatment regimen, especially if you have pre-existing medical conditions or are taking prescribed medications.

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