Independent reviews · Updated weekly Editorial & affiliate disclosures
HFL Health Findings Lab™

Iodine

An essential trace mineral required for the synthesis of thyroid hormones, regulating basal metabolic rate and cellular oxygen consumption.

Evidence-Based
Fact-Checked
Updated: Sep 23, 2026
Share this ingredient:
Clinical Profile

Quick Reference

Scientific Rating
5.0
/ 5.0
Standardized Form
Potassium Iodide or Standardized Kelp Extract

Iodine is a trace element that is physiologically indispensable for the human thyroid gland. It serves as the core structural building block for the thyroid hormones thyroxine (T4) and triiodothyronine (T3). These hormones are the primary regulators of the body's basal metabolic rate, mitochondrial energy production, and neurodevelopment. In dietary supplements, it is typically derived from marine sources (like kelp) or provided as potassium iodide to support healthy thyroid function and reverse metabolic sluggishness linked to deficiency.

Clinical Summary

Universally recognized as critical for preventing goiter, hypothyroidism, and developmental delays. Utilized clinically to correct deficiencies that lead to fatigue, weight gain, and metabolic dysregulation.

Dosage Guidelines

150mcg daily for baseline adult health; up to 290mcg during pregnancy or lactation.

Safety & Side Effects

Generally safe at recommended doses. Chronic megadosing can paradoxically induce hypothyroidism (Wolff-Chaikoff effect) or trigger hyperthyroidism (Jod-Basedow phenomenon).

Known Interactions

May interact with anti-thyroid medications (e.g., methimazole), ACE inhibitors, and potassium-sparing diuretics.

Scientific References

Medical Disclaimer

The information provided in this clinical review is for educational and informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

*These statements have not been evaluated by the Food and Drug Administration (FDA). This product or ingredient is not intended to diagnose, treat, cure, or prevent any disease.

Always consult your physician or other qualified health provider with any questions you may have regarding a medical condition, or before beginning any new diet, fitness, supplement, or treatment regimen, especially if you have pre-existing medical conditions or are taking prescribed medications.

Share this ingredient:

Articles discussing Iodine

Get new reviews in your inbox — weekly, never spammy.

Join our community of readers who use Health Findings Lab to cut through supplement marketing noise.